2-[(E)-(Morpholin-4-ylimino)methyl]-6-(morpholin-4-ylmethyl)phenol
نویسندگان
چکیده
The title compound, C16H23N3O3, contains two morpholine rings, each of which adopts a chair conformation. The mol-ecular conformation is stabilized by an intra-molecular O-H⋯N hydrogen bond, leading to a S(6) ring. In the crystal, mol-ecules are linked into zigzag chains along the c-axis direction by C-H⋯O and C-H⋯π inter-actions.
منابع مشابه
2-[(E)-(4-Methylphenyl)iminomethyl]-6-(morpholin-4-ylmethyl)phenol
In the title compound, C(19)H(22)N(2)O(2), the morpholine ring adopts an almost perfect normal chair conformation with puckering parameters Q(T), θ and ϕ of 0.5642 (18) Å, 177.32 (17) and ϕ = 10 (4)°, respectively. The two benzene rings make a dihedral angle of 42.67 (8)° with each other. An intra-molecular O-H⋯N hydrogen bond helps to stabilize the mol-ecular conformation. Aromatic C-H⋯π inter...
متن کامل2-Bromo-4-tert-butyl-6-[(pyridin-2-ylimino)methyl]phenol
In the title compound, C(16)H(17)BrN(2)O, the pyridine and benzene rings are almost coplanar [dihedral angle = 1.3 (2)°]. An intra-molecular O-H⋯Br inter-action forms an S(5) ring motif.
متن کامل4-[(2′-Cyanobiphenyl-4-yl)methyl]morpholin-4-ium tetrafluoridoborate
In the crystal structure of the title compound, C(18)H(19)N(2)O(+)·BF(4) (-), bifurcated N-H⋯(F,F) hydrogen bonds link the protonated 4'-morpholine-methyl-biphenyl-2-carbonitrile cations and slightly distorted tetra-fluoro-borate anions. π-π inter-actions [centroid-centroid distance = 3.805 (3) Å] help to consolidate the packing. The dihedral angle between the benzene rings in the cation is 57....
متن کامل4-[(2′-Cyanobiphenyl-4-yl)methyl]morpholin-4-ium perchlorate
In the title salt, C(18)H(19)N(2)O(+)·ClO(4) (-), the morpholinium ring adopts a chair conformation, while the two benzene rings make a dihedral angle of 62.65 (17)°. Inter-molecular N-H⋯N hydrogen bonds and weak C-H⋯O inter-actions occur in the crystal structure.
متن کاملNovel morpholin-3-one derivatives induced apoptosis and elevated the level of P53 and Fas in A549 lung cancer cells.
Previously, we found that nine kinds of new morpholin-3-one derivatives could inhibit the growth of A549 lung cancer cells in a dose-dependent manner, but how they performed their function remained unknown. In this paper, we studied the effects of the three more effective morpholin-3-one derivatives {4-(4-chlorophenyl)-6-((4-nitrophenoxy) methyl) morpholin-3-one (1); 6-(4-chlorophenoxy)-4-(4-me...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 69 شماره
صفحات -
تاریخ انتشار 2013